This USGS data release documents species distribution models for 419 fluvial fish species in their native ranges of the conterminous United States. Source data, supporting code and model results are documented in this data package. Boosted Regression Tree (BRT) models were used to develop presence/absence predictions for each of the National Hydrography Dataset Plus Version 2.1 stream segments within a species' native range. The predictions provided can be linked to the NHDPlusV2.1 geospatial dataset through the Common identifier of an NHDFlowline feature (COMID) to create a spatial depiction of the models. A readme file and metadata (xml) provide further information on included data and processing steps.