This data set represents monthly precipitation (in millimeters), and minimum and maximum temperature (in degrees Fahrenheit) over the period 1980-2023 compiled for two spatial components of the NHDPlus version 2 data suite (NHDPlusV2) for the conterminous United States; 1) individual reach catchments and 2) reach catchments accumulated upstream through the river network. This dataset can be linked to the NHDPlusV2 by the unique identifier COMID. Reach catchment information characterizes data at the local scale. Reach catchments are accumulated upstream through the river network using a modified routing database (Schwarz and Wieczorek, 2018) to navigate the NHDPlusV2 reach network to aggregate (accumulate) the metrics derived from the reach catchment scale. The variables included are precipitation (gridMet_CAT_pr and gridMet_TOT_pr), minimum temperature (gridMet_CAT_tmmn and gridMet_TOT_tmmn), and maximum temperature (gridMet_CAT_tmmx and gridMet_TOT_tmmx) summarized from gridMET (Abatzoglou, 2011). Summaries are provided for five regions corresponding to NHDPlusV2 vector processing units (VPUs): VPU 02, VPU 03w, VPU 04, VPU 14, and VPU 17.