The data contain yearly modeled estimates of Pacific salmon escapement (in annual metric tons of wet mass) from 1976 to 2015 across four regions of western North America. A second data file contains modeled estimates of contaminant or nutrient concentrations in Pacific Salmon. The modeled estimates were derived from Bayesian generalized linear models (contaminant or nutrient concentrations) or from Bayesian generalized additive models (Salmon Escapement).