The High Plains aquifer extends from approximately 32 to 44 degrees north latitude and 96 degrees 30 minutes to 106 degrees west longitude. The aquifer underlies about 175,000 square miles in parts of Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming. This dataset consists of a raster of estimated water-level changes for the High Plains aquifer from pre-irrigation season 2017 to pre-irrigation season 2019. This digital dataset was created using water-level measurements from 7,195 wells measured in both 2017 and 2019. The map was reviewed for consistency with the relevant data at a scale of 1:1,000,000. Negative raster-cell values correspond to decline in water level and positive raster-cell values correspond to water-level rise.