This dataset is a digital elevation model (DEM) comprising topographic and bathymetric data for an approximately 500 meter (m) reach of the Kalamazoo River upstream of Plainwell, Michigan (MI). The DEM was developed from elevation data collected by several different methods. Bathymetric data in the river channel were collected in October 2021 with a single beam sonar and Acoustic Current Doppler Profiler operated along 2 longitudinal transects and 48 cross-sectional transects, respectively. River bank topographic data were collected with a backpack-mounted terrestrial lidar unit concurrently with the bathymetric data. Lidar points were classified by a combination of automated and manual methods. Floodplain elevations were obtained from aerial lidar data collected in 2015. All ground points from the respective datasets were projected to the same coordinate system and used to generate a DEM with 1m resolution covering the channel bed, banks, and floodplain, and valley walls through the reference reach.