Here we provide information for the DESIS and PRISMA Derived Spectral Library of Agricultural Crops in California which was developed using DESIS and PRISMA hyperspectral data acquired for 2020. The DESIS images used for this dataset are available through the German Aerospace Center and Teledyne Brown (2022). PRISMA images are available through the Italian Space Agency (ASI) (2022). The crop type data and confidence layer for the year 2020 can be accessed through the USDA National Agricultural Statistics Service (2022). The DESIS and PRISMA Derived Spectral Library of Agricultural Crops dataset characteristics are described below, with DESIS and PRISMA data provided in two separate CSV files. Related Primary Publication: Aneece, I.P., and Thenkabail, P.S., 2022, New generation hyperspectral sensor (DESIS and PRISMA) performances in agriculture.