Low-altitude (80 and 100 meters above ground level) digital images were collected by the USGS Woods Hole Coastal and Marine Science Center (WHCMSC) Aerial Imaging and Mapping Group (AIMG) over an area of the Plum Island Estuary and Parker River National Wildlife Refuge (NWR) in Massachusetts on November 14, 2017 and March 28, 2019 to document marsh stability over time and quantify sediment movement. A 3DR Solo uncrewed aircraft systems (UAS) was equipped with either a Ricoh GR II digital camera for true color photos, which can be used to produce digital elevation models and ortho images, or a MicaSense RedEdge multispectral camera for five-banded imagery (blue, green, red, red edge, and near-infrared spectral bands), which can be used to classify vegetation. The MicaSense camera covered a smaller subsection of the same polygonal area of the marsh that the Ricoh imaged. Some photographs contain black and white targets used as ground control points (GCPs), which were surveyed by a field crew with a high-precision Real-Time Kinematic Global Positioning System. This data release includes the original images from both cameras, as well as a CSV file containing the latitude and longitude coordinates, in Universal Transverse Mercator Zone 19N referenced to the North American Datum of 1983, of the ground control points needed to complete any photogrammetry projects using the original photographs, and GPS transect points used to evaluate the photogrammetry products created.