Mule deer in the southern Wyoming Range population winter north of Evanston in the relatively low mountains between Kemmerer, Wyoming, and Woodruff Narrows Reservoir along the Utah border. Many deer in this population migrate north more than 100 mi (161 km) to summer ranges in the Wyoming Range surrounding Afton, Wyoming. Migrations in this population are not limited to Wyoming, with at least one deer summering in the Caribou Range in Idaho. Challenges for this population include highway and train mortality, especially along U.S. Highway 30. A number of highway underpasses were constructed between 2001 and 2008 along U.S. Highway 30 at Nugget Canyon, which has significantly reduced vehicle-caused mortality. These data provide the location of migration routes for mule deer (Odocoileus hemionus) in the Wyoming Range South population in Wyoming. They were developed from Brownian bridge movement models using 237 migration sequences collected from a sample size of 63 animals comprising GPS locations collected every 2-8 hours.