Mule deer within the Owl Creek/Meeteetse herd make a number of medium- to long-distance migrations west into the Shoshone National Forest. These migrations originate on the sagebrush grasslands just southwest and west of Meeteetse, Wyoming, where this population winters. In spring, an estimated 4,100 deer leave these foothills and travel into the rugged Absaroka mountain range. These journeys, across challenging natural terrain, range an average of 27 miles and include navigating fast moving rivers, such as the Greybull River, and over high mountains passes like Bear Creek and East Fork Pass—the highest at 12,230 feet in elevation. The longest migration is 70 miles to the Dunoir Valley northwest of Dubois. Although the private lands that comprise winter range and low-eleveation route segments are at risk of residential development, once deer cross onto the National Forest they encounter few human-created obstacles in this remote wilderness environment. These data provide the location of migration routes for mule deer (Odocoileus hemionus) in the Owl Creek/Meeteetse herd in Wyoming. They were developed from Brownian bridge movement models using 86 migration sequences collected from a sample size of 32 animals comprising GPS locations collected every 2-8 hours.