Information on pesticide applications, crop pests, and phylogenetic affinities between Californian crops and regional native plants were compiled. Data was collected to inform models of pesticide applications and host use of pests among California's 93 major crops. Pesticide data was assembled from California Department of Pesticide Regulation records, pest information was assembled from the California Integrated Pest Management database, and phylogenetic affinities were based on a supertree of plants in the Jepson Manual assembled based on the Zanne et al 2014 mega-phylogeny of seed plants.