Nitrogen, phosphorus, and suspended-sediment loads, and changes in loads, in rivers across the Chesapeake Bay watershed have been calculated using monitoring data from the Chesapeake Bay Nontidal Network (NTN) stations for the period 1985 through 2018 Nutrient and suspended-sediment loads and changes in loads were determined by applying a weighted regression approach called WRTDS (Weighted Regression on Time, Discharge, and Season). A recently published extension of WRTDS allows users to separate these estimates into high- and low-flow conditions. This data release contains (1) a table of daily high- and low-flow concentration and load estimates for NTN stations between 1985 - 2018 and (2) an R file that contains the flow-separation functions. First posted: September 2020 (available from author) Revised: November 2021 (version 1.1)