This data release provides multi-element data for drill core samples from the Mesoproterozoic Nonesuch Formation and Copper Harbor Conglomerate at the Copperwood copper deposit, Michigan, USA. Copper was determined by assay, and sulfur by inductively coupled plasma-optical emission spectrometry (ICP-OES) after aqua regia digestion for most samples. Multi-element whole rock analyses were determined for selected samples. The Copperwood copper deposit is a sediment-hosted stratiform copper deposit in the Presque Isle Syncline of the Upper Peninsula of Michigan. The deposit has a 2018 mineral resource estimate of 42.2 million metric tons (Mt) of measured plus indicated mineral resources in the Lower Copper Bearing Sequence at an average grade of 1.60 percent Cu and 3.84 grams per ton (g/t) Ag. The measured plus indicated mineral resource in the Upper Copper Bearing Sequence is estimated to be 7.1 Mt at an average grade of 1.21 percent Cu and 3.26 g/t Ag (Gignac, 2018). The mineral reserves for the Copperwood Project are estimated at 25.4 Mt at an average grade of 1.43 percent Cu and 3.83 g/t Ag (Gignac, 2018).