This dataset is the assembled analytical results of geochemical, petrographic, and geochronologic data for samples, principally those of unmineralized Tertiary volcanic rocks, from the Tonopah, Divide, and Goldfield mining districts of west-central Nevada. Much of the data presented here for the Tonopah and Divide districts are for samples collected by Bonham and Garside (1979) during geologic mapping in and around those districts, whereas much of that for samples from the Goldfield district were obtained by Ashley (1974; 1979; 1990). Additional data were derived from samples collected between 2012–2017, as part of the U.S. Geological Survey Mineral Resources Program funded project titled: “Magmatic-tectonic history and component sources of major precious metal deposits in the southern Walker Lane”. A small amount of additional geochemical data for samples from each of the districts were compiled from other sources.