This data release supports the following publication: Mast, M. A., 2018, Estimating metal concentrations with regression analysis and water-quality surrogates at nine sites on the Animas and San Juan Rivers, Colorado, New Mexico, and Utah: U.S. Geological Survey Scientific Investigations Report 2018-5116. The U.S. Geological Survey (USGS), in cooperation with the U. S. Environmental Protection Agency (EPA), developed site-specific regression models to estimate concentrations of selected metals at nine USGS streamflow-gaging stations along the Animas and San Juan Rivers. Multiple linear-regression models were developed by relating metal concentrations in discrete water-quality samples to continuously monitored streamflow and surrogate parameters including specific conductance, pH, turbidity, and water temperature. Models were developed for dissolved and total concentrations of aluminum, arsenic, cadmium, iron, lead, manganese, and zinc using water-quality samples collected during 2005–17 by several agencies, using different collection methods and analytical laboratories. Calibration datasets in comma-separated format (CSV) include the variables of sampling date and time, metal concentrations (in micrograms per liter), stream discharge (in cubic feet per second), specific conductance (in microsiemens per centimeter at 25 degrees Celsius), pH, water temperature (in degrees Celsius), turbidity (in nephelometric turbidity units), and calculated seasonal terms based on Julian day. Surrogate parameters and discrete water-quality samples were used from nine sites including Cement Creek at Silverton, Colo. (USGS station 09358550); Animas River below Silverton, Colo. (USGS station 09359020); Animas River at Durango, Colo. (USGS station 09361500); Animas River Near Cedar Hill, N. Mex. (USGS station 09363500); Animas River below Aztec, N. Mex. (USGS station 09364010); San Juan River at Farmington, N. Mex. (USGS station 09365000); San Juan River at Shiprock, N. Mex (USGS Station 09368000); San Juan River at Four Corners, Colo. (USGS station 09371010); and San Juan River near Bluff, Utah (USGS station 09379500). Model archive summaries in pdf format include model statistics, data, and plots and were generated using a R script developed by USGS Kansas Water Science Center available at https://patrickeslick.github.io/ModelArchiveSummary/. A description of each USGS streamflow gaging station along with information about the calibration datasets also are provided.