The statistically-based estimates of streamflow included here are for the headwater watersheds in the study area described in LaFontaine and others (2019), and were developed using the ordinary kriging methodology described in Farmer (2016). There are four files included that describe the maximum, minimum, mean, and median estimated streamflow for each headwater on a daily time step for the period 10/1/1980-9/30/2010. A GIS shapefile of the headwaters is also included here. Farmer, W.H., 2016, Ordinary kriging as a tool to estimate historical daily streamflow records: Hydrology and Earth System Sciences, v. 20, no. 7, p. 2721-2735, accessed September 27, 2017, at https://doi.org/10.5194/hess-20-2721-2016. LaFontaine, J.H., Hart, R.M., Hay, L.E., Farmer, W.H., Bock, A.R., Viger, R.J., Markstrom, S.L., Regan, R.S., and Driscoll, J.M., in review, Simulation of Water Availability in the Southeastern United States for Historical and Potential Future Climate and Land-Cover Conditions: U.S. Geological Survey Scientific Investigations Report, 2019-5039, 83 p., https://doi.org/10.3133/sir20195039.