These replicate data support the findings described in the publication, "A comparison of four pore water sampling methods for mixed metals and dissolved organic carbon, and implications for sediment toxicity evaluations" by Danielle Cleveland, William G. Brumbaugh, and Donald D. MacDonald (Environmental Toxicology and Chemistry 2017). The data represent comparison of four commonly-applied techniques for obtaining pore water samples for the quantification of nickel, copper, zinc, arsenic, cadmium, lead and dissolved organic carbon (DOC), including peepers, push points, centrifugation, and diffusive gradients in thin films (DGTs). The methods were evaluated at low and high concentrations of metals in three sediments having different concentrations of total organic carbon, acid volatile sulfide, and particle size.